Insulin-Like Growth Factor-1, commonly referred to as IGF-1 is a polypeptide hormone that belongs to the growth factor hormone family. This is a naturally produced hormone in all human beings with production primarily occurring in the liver, and to a degree in the peripheral tissues. However, synthetic versions do exist and are produced by recombinant DNA technology.
IGF-1 is a highly anabolic hormone that affects numerous areas of the human body. It also shares an important relationship with Human Growth Hormone (HGH), and on a structural basis is similar to insulin. There are several synthetic IGF-1 products on the market, but perhaps the most well-known is Increlex manufactured by Tercia INC.
In a therapeutic setting IGF-1 is primarily used to treat IGF-1 deficiencies. However, it is also used in patients who do not respond to HGH. With this type of therapy, the individual may very well have plenty of HGH in his system but for one reason or another is not responding to the hormone. IGF-1 treatment for this purpose is FDA approved, but it is considered very controversial by some medical professionals due to the possible metabolic effects that could occur. Then we have performance enhancement, and in recent years IGF-1 has become an important hormone in this arena. It is powerfully anabolic, will carry strong recovery properties and has become a favorite of many in bodybuilding circles.